Studying 1,899 subjects with a confirmed diagnosis of RA (fulfilling ACR criteria) and 2,145 controls (randomly selected and matched for age, sex and residential area), investigators concluded that the odds ratio (OR) for developing RA was 0.8 (0.7-1.0) for those who consumed oily fish 1-7 times per week or 1-3 times per month, compared with those who never, or seldom consumed oily fish. Interestingly, no significant association with RA risk was observed for consumption of fish oil supplements. Tobacco smoking is an established risk factor for RA, but the investigators found that there is a dose dependency for the level of smoking (i.e. the number of cigarettes smoked across a given period) on the odds ratio of developing anti-citrulline (anti-CCP) positive RA. The highest odds ratios were seen in those carrying a risk variant of the susceptibility gene PTPN22. In the study, 1,240 cases and 798 controls were identified as smokers from a total group of 1,419 cases and 1,674 controls via an extensive questionnaire regarding lifestyle factors, including smoking habits.
These subjects were then classified into three different groups according to the number of pack years smoked - less then 10, 10-20 or more than 20 pack years (where one pack-year is equivalent to having smoked one pack per day for one year) and genotyped to determine the presence of the PTPN22 risk allele. Psychosocial stress at work, defined as low decision latitude (or low level of control) was found to be associated with a higher risk for RA. Collected via a validated questionnaire, this was demonstrated in both self-reported data and JEM (job exposure matrix)-derived data.These results were only marginally changed when the investigators adjusted the odds ratios for social class and smoking for the 1,221 cases and 1,454 controls who participated in the study.
Mrs Annmarie Wesley of the Institute of Environmental Medicine, Stockholm, Sweden, EIRA investigator and lead author of the oily fish intake study, commented: "The findings from these studies add to an increasing body of evidence to support the assertion that lifestyle modifications can have a significant impact on an individual's risk for developing RA, one of the most common autoimmune diseases, affecting approximately 1pc of adults worldwide.”
Sunday, June 22, 2008
Arthiritis risks reduced by Oily fish
Posted by
jawed iqbal
at
12:33 AM
Honey - a magic remedy
You have been keeping a hawk's eye on your body weight and are a regular at the gym. You also drink lots of water and fiber-rich diet. You even follow experts' advice on taking care of your hair and skin. But what about those eyes? How do you protect them from the stress that is caused by working long hours before the computer? Well, here's an easy answer to that: Take the traditional route add a little honey to your daily diet.
Yes, whether its your grandmother, or the neighbourhood doctor, everybody will agree to this fact that honey not only helps protect the eyes, but also help improve your eyesight. While there are plenty of home remedies from honey, we bring you a few here: Perry Kharpuri is a researcher based in Shillong, a place well-known for it's large-scale honey production. Perry's advice is , "mix two teaspoons of honey with carrot juice and consume regularly", to improve your eye sight and cure problems such as watering of eyes. In cold, cough and congested chest, two teaspoons of honey with equal quantity of ginger juice should be consumed frequently. This is one of the oldest and most popular remedies that millions of Indians already follow. The other such popular remedy is to take one spoon of fresh honey mixed with the juice of half a lemon in a glass of lukewarm water in order to get cured of constipation, hyperacidity and obesity. Now, Swapan Debnath, a homeopath says that honey can help control your BP as well. According to him, two teaspoons of honey should be mixed with one teaspoon of garlic juice and taken on a regular basis. Maheep Kohli owns a bee farm in Moga,
Posted by
jawed iqbal
at
12:30 AM